Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress and antibiotics. Many Pseudomonas strains produce fun...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Najarzadeh, Zahra, Mohammad-Beigi, Hossein, Nedergaard Pedersen, Jannik, Christiansen, Gunna, Sønderby, Thorbjørn Vincent, Shojaosadati, Seyed Abbas, Morshedi, Dina, Strømgaard, Kristian, Meisl, Georg, Sutherland, Duncan, Skov Pedersen, Jan, Otzen, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920965/
https://ncbi.nlm.nih.gov/pubmed/31717821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110659
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