Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress and antibiotics. Many Pseudomonas strains produce fun...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Najarzadeh, Zahra, Mohammad-Beigi, Hossein, Nedergaard Pedersen, Jannik, Christiansen, Gunna, Sønderby, Thorbjørn Vincent, Shojaosadati, Seyed Abbas, Morshedi, Dina, Strømgaard, Kristian, Meisl, Georg, Sutherland, Duncan, Skov Pedersen, Jan, Otzen, Daniel E.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920965/
https://ncbi.nlm.nih.gov/pubmed/31717821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110659
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