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Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
Aggregation of α-synuclein (αSN) is implicated in neuronal degeneration in Parkinson's disease and has prompted searches for natural compounds inhibiting αSN aggregation and reducing its tendency to form toxic oligomers. Oil from the olive tree (Olea europaea L.) represents the main source of f...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422090/ https://ncbi.nlm.nih.gov/pubmed/30655291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005723 |
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