How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicity in Vitro

Oligomeric species of various proteins are linked to the pathogenesis of different neurodegenerative disorders. Consequently, there is intense focus on the discovery of novel inhibitors, e.g. small molecules and antibodies, to inhibit the formation and block the toxicity of oligomers. In Parkinson d...

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Détails bibliographiques
Auteurs principaux: Lorenzen, Nikolai, Nielsen, Søren B., Yoshimura, Yuichi, Vad, Brian S., Andersen, Camilla Bertel, Betzer, Cristine, Kaspersen, Jørn D., Christiansen, Gunna, Pedersen, Jan S., Jensen, Poul Henning, Mulder, Frans A. A., Otzen, Daniel E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118093/
https://ncbi.nlm.nih.gov/pubmed/24907278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554667
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