Epigallocatechin Gallate Remodels Overexpressed Functional Amyloids in Pseudomonas aeruginosa and Increases Biofilm Susceptibility to Antibiotic Treatment

Epigallocatechin-3-gallate (EGCG) is the major polyphenol in green tea. It has antimicrobial properties and disrupts the ordered structure of amyloid fibrils involved in human disease. The antimicrobial effect of EGCG against the opportunistic pathogen Pseudomonas aeruginosa has been shown to involv...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Stenvang, Marcel, Dueholm, Morten S., Vad, Brian S., Seviour, Thomas, Zeng, Guanghong, Geifman-Shochat, Susana, Søndergaard, Mads T., Christiansen, Gunna, Meyer, Rikke Louise, Kjelleberg, Staffan, Nielsen, Per Halkjær, Otzen, Daniel E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Protein Structure and Folding
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159513/
https://ncbi.nlm.nih.gov/pubmed/27784787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.739953
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