Epigallocatechin Gallate Remodels Overexpressed Functional Amyloids in Pseudomonas aeruginosa and Increases Biofilm Susceptibility to Antibiotic Treatment

Epigallocatechin-3-gallate (EGCG) is the major polyphenol in green tea. It has antimicrobial properties and disrupts the ordered structure of amyloid fibrils involved in human disease. The antimicrobial effect of EGCG against the opportunistic pathogen Pseudomonas aeruginosa has been shown to involv...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Stenvang, Marcel, Dueholm, Morten S., Vad, Brian S., Seviour, Thomas, Zeng, Guanghong, Geifman-Shochat, Susana, Søndergaard, Mads T., Christiansen, Gunna, Meyer, Rikke Louise, Kjelleberg, Staffan, Nielsen, Per Halkjær, Otzen, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159513/
https://ncbi.nlm.nih.gov/pubmed/27784787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.739953
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