How epigallocatechin gallate binds and assembles oligomeric forms of human alpha-synuclein

The intrinsically disordered human protein α-synuclein (αSN) can self-associate into oligomers and amyloid fibrils. Several lines of evidence suggest that oligomeric αSN is cytotoxic, making it important to devise strategies to either prevent oligomer formation and/or inhibit the ensuing toxicity. (...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Andersen, Camilla B., Yoshimura, Yuichi, Nielsen, Janni, Otzen, Daniel E., Mulder, Frans A.A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191297/
https://ncbi.nlm.nih.gov/pubmed/34019875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100788
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker