Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

Aggregation of α-synuclein (αSN) is implicated in neuronal degeneration in Parkinson's disease and has prompted searches for natural compounds inhibiting αSN aggregation and reducing its tendency to form toxic oligomers. Oil from the olive tree (Olea europaea L.) represents the main source of f...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Mohammad-Beigi, Hossein, Aliakbari, Farhang, Sahin, Cagla, Lomax, Charlotte, Tawfike, Ahmed, Schafer, Nicholas P., Amiri-Nowdijeh, Alireza, Eskandari, Hoda, Møller, Ian Max, Hosseini-Mazinani, Mehdi, Christiansen, Gunna, Ward, Jane L., Morshedi, Dina, Otzen, Daniel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422090/
https://ncbi.nlm.nih.gov/pubmed/30655291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005723
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