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Histone Chaperone FACT and Curaxins: Effects on Genome Structure and Function
The histone chaperone FACT plays important roles in essentially every chromatin-associated process and is an important indirect target of the curaxin class of anti-cancer drugs. Curaxins are aromatiс compounds that intercalate into DNA and can trap FACT in bulk chromatin, thus interfering with its d...
Uloženo v:
| Vydáno v: | J Cancer Metastasis Treat |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6919649/ https://ncbi.nlm.nih.gov/pubmed/31853507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/2394-4722.2019.31 |
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