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Histone Chaperone FACT and Curaxins: Effects on Genome Structure and Function
The histone chaperone FACT plays important roles in essentially every chromatin-associated process and is an important indirect target of the curaxin class of anti-cancer drugs. Curaxins are aromatiс compounds that intercalate into DNA and can trap FACT in bulk chromatin, thus interfering with its d...
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| 出版年: | J Cancer Metastasis Treat |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6919649/ https://ncbi.nlm.nih.gov/pubmed/31853507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/2394-4722.2019.31 |
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