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Histone chaperone FACT is essential to overcome replication stress in mammalian cells
The histone chaperone FACT is upregulated during mammary tumorigenesis and necessary for the viability and growth of breast tumor cells. We established that only proliferating tumor cells are sensitive to FACT knockdown, suggesting that FACT functions during DNA replication in tumor cells but not in...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7343669/ https://ncbi.nlm.nih.gov/pubmed/32533099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1346-9 |
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