TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1

The tripartite motif (TRIM) proteins constitute a family of ubiquitin E3 ligases involved in a multitude of cellular processes, including protein homeostasis and autophagy. TRIM32 is characterized by six protein–protein interaction domains termed NHL, various point mutations in which are associated...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Overå, Katrine Stange, Garcia-Garcia, Juncal, Bhujabal, Zambarlal, Jain, Ashish, Øvervatn, Aud, Larsen, Kenneth Bowitz, Deretic, Vojo, Johansen, Terje, Lamark, Trond, Sjøttem, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918758/
https://ncbi.nlm.nih.gov/pubmed/31685529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.236596
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky