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Quantifying the benefit offered by transcript assembly with Scallop-LR on single-molecule long reads

Single-molecule long-read sequencing has been used to improve mRNA isoform identification. However, not all single-molecule long reads represent full transcripts due to incomplete cDNA synthesis and sequencing length limits. This drives a need for long-read transcript assembly. By adding long-read-s...

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Vydáno v:Genome Biol
Hlavní autoři: Tung, Laura H., Shao, Mingfu, Kingsford, Carl
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918626/
https://ncbi.nlm.nih.gov/pubmed/31849338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1883-0
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