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Gcn5-mediated histone acetylation governs nucleosome dynamics in spermiogenesis

During mammalian spermatogenesis, germ cell chromatin undergoes dramatic histone acetylation-mediated reorganization, whereby 90-99% of histones are evicted. Given the potential role of retained histones in fertility and embryonic development, the genomic location of retained nucleosomes is of great...

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Dades bibliogràfiques
Publicat a:Dev Cell
Autors principals: Luense, Lacey J., Donahue, Greg, Lin-Shiao, Enrique, Rangel, Richard, Weller, Angela H., Bartolomei, Marisa S., Berger, Shelley L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917834/
https://ncbi.nlm.nih.gov/pubmed/31761669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.10.024
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