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Histone modification signatures in human sperm distinguish clinical abnormalities

PURPOSE: Alternations to the paternal epigenome, specifically the components of sperm chromatin, can lead to infertility in humans and potentially transmit aberrant information to the embryo. One key component of sperm chromatin is the post-translational modification of histones (PTMs). We previousl...

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Bibliografski detalji
Izdano u:J Assist Reprod Genet
Glavni autori: Schon, Samantha B., Luense, Lacey J., Wang, Xiaoshi, Bartolomei, Marisa S., Coutifaris, Christos, Garcia, Benjamin A., Berger, Shelley L.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420512/
https://ncbi.nlm.nih.gov/pubmed/30397898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-018-1354-7
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