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Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells

BACKGROUND: During the process of spermatogenesis, male germ cells undergo dramatic chromatin reorganization, whereby most histones are replaced by protamines, as part of the pathway to compact the genome into the small nuclear volume of the sperm head. Remarkably, approximately 90 % (human) to 95 %...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Luense, Lacey J., Wang, Xiaoshi, Schon, Samantha B., Weller, Angela H., Lin Shiao, Enrique, Bryant, Jessica M., Bartolomei, Marisa S., Coutifaris, Christos, Garcia, Benjamin A., Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915177/
https://ncbi.nlm.nih.gov/pubmed/27330565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0072-6
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