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RNA binding to CBP stimulates histone acetylation and transcription

CBP/p300 are transcription co-activators whose binding is a signature of enhancers, cis-regulatory elements that control patterns of gene expression in multicellular organisms. Active enhancers produce bi-directional enhancer RNAs (eRNAs) and display CBP/p300 dependent histone acetylation. Here, we...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Bose, Daniel A, Donahue, Greg, Reinberg, Danny, Shiekhattar, Ramin, Bonasio, Roberto, Berger, Shelley L
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325706/
https://ncbi.nlm.nih.gov/pubmed/28086087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.020
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