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Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors
The D2 dopamine receptor and the serotonin 5-hydroxytryptamine 2A receptor (5-HT2A) are closely-related G-protein–coupled receptors (GPCRs) from the class A bioamine subfamily. Despite structural similarity, they respond to distinct ligands through distinct downstream pathways, whose dysregulation i...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6916503/ https://ncbi.nlm.nih.gov/pubmed/31676688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008068 |
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