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Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

BACKGROUND: Pseudomonas aeruginosa (PA) is an opportunistic Gram-negative bacterium that causes serious life threatening and nosocomial infections including pneumonia. PA has the ability to alter host genome to facilitate its invasion, thus increasing the virulence of the organism. Sphingosine-1- ph...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Ebenezer, David L., Fu, Panfeng, Krishnan, Yashaswin, Maienschein-Cline, Mark, Hu, Hong, Jung, Segun, Madduri, Ravi, Arbieva, Zarema, Harijith, Anantha, Natarajan, Viswanathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916461/
https://ncbi.nlm.nih.gov/pubmed/31842752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6367-9
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