Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

BACKGROUND: Pseudomonas aeruginosa (PA) is an opportunistic Gram-negative bacterium that causes serious life threatening and nosocomial infections including pneumonia. PA has the ability to alter host genome to facilitate its invasion, thus increasing the virulence of the organism. Sphingosine-1- ph...

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Vydáno v:BMC Genomics
Hlavní autoři: Ebenezer, David L., Fu, Panfeng, Krishnan, Yashaswin, Maienschein-Cline, Mark, Hu, Hong, Jung, Segun, Madduri, Ravi, Arbieva, Zarema, Harijith, Anantha, Natarajan, Viswanathan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916461/
https://ncbi.nlm.nih.gov/pubmed/31842752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6367-9
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