Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

BACKGROUND: Pseudomonas aeruginosa (PA) is an opportunistic Gram-negative bacterium that causes serious life threatening and nosocomial infections including pneumonia. PA has the ability to alter host genome to facilitate its invasion, thus increasing the virulence of the organism. Sphingosine-1- ph...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Ebenezer, David L., Fu, Panfeng, Krishnan, Yashaswin, Maienschein-Cline, Mark, Hu, Hong, Jung, Segun, Madduri, Ravi, Arbieva, Zarema, Harijith, Anantha, Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916461/
https://ncbi.nlm.nih.gov/pubmed/31842752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6367-9
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