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Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their progeny past the pluripotency stage

BACKGROUND: Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or inducible variants of these recombinases are expressed under the control of either lineage-specific or ubiquitous promoters. However, t...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Kuzmin, Andrey A., Ermakova, Veronika V., Sinenko, Sergey A., Ponomartsev, Sergey V., Starkova, Tatiana Y., Skvortsova, Elena V., Cherepanova, Olga, Tomilin, Alexey N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916430/
https://ncbi.nlm.nih.gov/pubmed/31843009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1520-6
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