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Immortalized murine fibroblast cell lines are refractory to reprogramming to pluripotent state

To date different cell types of various mammalian species have been reprogrammed to induced pluripotent stem cells (iPSCs) using Yamanaka's cocktail of transcription factors (Oct4, Klf4, Sox2, and cMyc). It has been shown that several primary human cancer cell lines could be reprogrammed to iPS...

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Foilsithe in:Oncotarget
Main Authors: Skvortsova, Elena V., Sinenko, Sergey A., Tomilin, Alexey N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219659/
https://ncbi.nlm.nih.gov/pubmed/30443291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26235
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