Transfer of Synthetic Human Chromosome into Human Induced Pluripotent Stem Cells for Biomedical Applications

Alphoid(tetO)-type human artificial chromosome (HAC) has been recently synthetized as a novel class of gene delivery vectors for induced pluripotent stem cell (iPSC)-based tissue replacement therapeutic approach. This HAC vector was designed to deliver copies of genes into patients with genetic dise...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sinenko, Sergey A., Skvortsova, Elena V., Liskovykh, Mikhail A., Ponomartsev, Sergey V., Kuzmin, Andrey A., Khudiakov, Aleksandr A., Malashicheva, Anna B., Alenina, Natalia, Larionov, Vladimir, Kouprina, Natalay, Tomilin, Alexey N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316689/
https://ncbi.nlm.nih.gov/pubmed/30544831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7120261
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