On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding many ribosomal proteins (RPs) in axons, far away from neuronal cell bodies. Here, we report a physical and functional interaction between locally synthesized RPs and...

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Udgivet i:Cell Rep
Main Authors: Shigeoka, Toshiaki, Koppers, Max, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Cagnetta, Roberta, Dwivedy, Asha, de Freitas Nascimento, Janaina, van Tartwijk, Francesca W., Ströhl, Florian, Cioni, Jean-Michel, Schaeffer, Julia, Carrington, Mark, Kaminski, Clemens F., Jung, Hosung, Harris, William A., Holt, Christine E.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915326/
https://ncbi.nlm.nih.gov/pubmed/31825839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.025
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