On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding many ribosomal proteins (RPs) in axons, far away from neuronal cell bodies. Here, we report a physical and functional interaction between locally synthesized RPs and...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Shigeoka, Toshiaki, Koppers, Max, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Cagnetta, Roberta, Dwivedy, Asha, de Freitas Nascimento, Janaina, van Tartwijk, Francesca W., Ströhl, Florian, Cioni, Jean-Michel, Schaeffer, Julia, Carrington, Mark, Kaminski, Clemens F., Jung, Hosung, Harris, William A., Holt, Christine E.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915326/
https://ncbi.nlm.nih.gov/pubmed/31825839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.025
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