Dynamic Axonal Translation in Developing and Mature Visual Circuits

Local mRNA translation mediates the adaptive responses of axons to extrinsic signals, but direct evidence that it occurs in mammalian CNS axons in vivo is scant. We developed an axon-TRAP-RiboTag approach in mouse that allows deep-sequencing analysis of ribosome-bound mRNAs in the retinal ganglion c...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Shigeoka, Toshiaki, Jung, Hosung, Jung, Jane, Turner-Bridger, Benita, Ohk, Jiyeon, Lin, Julie Qiaojin, Amieux, Paul S., Holt, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930487/
https://ncbi.nlm.nih.gov/pubmed/27321671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.029
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