Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

Local translation regulates the axonal proteome, playing an important role in neuronal wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites for translation, however, is not understood. Here we report that RNA granules associate with endosomes along the axons of r...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Cioni, Jean-Michel, Lin, Julie Qiaojin, Holtermann, Anne V., Koppers, Max, Jakobs, Maximilian A.H., Azizi, Afnan, Turner-Bridger, Benita, Shigeoka, Toshiaki, Franze, Kristian, Harris, William A., Holt, Christine E.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
https://ncbi.nlm.nih.gov/pubmed/30612743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.030
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