Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

Local translation regulates the axonal proteome, playing an important role in neuronal wiring and axon maintenance. How axonal mRNAs are localized to specific subcellular sites for translation, however, is not understood. Here we report that RNA granules associate with endosomes along the axons of r...

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Publicat a:Cell
Autors principals: Cioni, Jean-Michel, Lin, Julie Qiaojin, Holtermann, Anne V., Koppers, Max, Jakobs, Maximilian A.H., Azizi, Afnan, Turner-Bridger, Benita, Shigeoka, Toshiaki, Franze, Kristian, Harris, William A., Holt, Christine E.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
https://ncbi.nlm.nih.gov/pubmed/30612743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.030
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