Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

Extrinsic cues trigger the local translation of specific mRNAs in growing axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals to local translation but it is not known how broadly this mechanism operates, nor whether it can selecti...

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Veröffentlicht in:eLife
Hauptverfasser: Koppers, Max, Cagnetta, Roberta, Shigeoka, Toshiaki, Wunderlich, Lucia CS, Vallejo-Ramirez, Pedro, Qiaojin Lin, Julie, Zhao, Sixian, Jakobs, Maximilian AH, Dwivedy, Asha, Minett, Michael S, Bellon, Anaïs, Kaminski, Clemens F, Harris, William A, Flanagan, John G, Holt, Christine E
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2019
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894925/
https://ncbi.nlm.nih.gov/pubmed/31746735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48718
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