Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

Extrinsic cues trigger the local translation of specific mRNAs in growing axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals to local translation but it is not known how broadly this mechanism operates, nor whether it can selecti...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Koppers, Max, Cagnetta, Roberta, Shigeoka, Toshiaki, Wunderlich, Lucia CS, Vallejo-Ramirez, Pedro, Qiaojin Lin, Julie, Zhao, Sixian, Jakobs, Maximilian AH, Dwivedy, Asha, Minett, Michael S, Bellon, Anaïs, Kaminski, Clemens F, Harris, William A, Flanagan, John G, Holt, Christine E
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894925/
https://ncbi.nlm.nih.gov/pubmed/31746735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48718
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