Dynamic Axonal Translation in Developing and Mature Visual Circuits

Local mRNA translation mediates the adaptive responses of axons to extrinsic signals, but direct evidence that it occurs in mammalian CNS axons in vivo is scant. We developed an axon-TRAP-RiboTag approach in mouse that allows deep-sequencing analysis of ribosome-bound mRNAs in the retinal ganglion c...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Shigeoka, Toshiaki, Jung, Hosung, Jung, Jane, Turner-Bridger, Benita, Ohk, Jiyeon, Lin, Julie Qiaojin, Amieux, Paul S., Holt, Christine E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930487/
https://ncbi.nlm.nih.gov/pubmed/27321671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.029
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