Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons

Local mRNA translation occurs in growing axons enabling precise control of the proteome in response to signals. To measure quantitatively the spatiotemporal dynamics of protein synthesis in growth cones, we further developed a technique for single molecule translation imaging (SMTI). We report that...

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Pubblicato in:Sci Rep
Autori principali: Ströhl, Florian, Lin, Julie Qiaojin, Laine, Romain F., Wong, Hovy Ho-Wai, Urbančič, Vasja, Cagnetta, Roberta, Holt, Christine E., Kaminski, Clemens F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428787/
https://ncbi.nlm.nih.gov/pubmed/28386060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00695-7
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