Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons

Local mRNA translation occurs in growing axons enabling precise control of the proteome in response to signals. To measure quantitatively the spatiotemporal dynamics of protein synthesis in growth cones, we further developed a technique for single molecule translation imaging (SMTI). We report that...

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Published in:Sci Rep
Main Authors: Ströhl, Florian, Lin, Julie Qiaojin, Laine, Romain F., Wong, Hovy Ho-Wai, Urbančič, Vasja, Cagnetta, Roberta, Holt, Christine E., Kaminski, Clemens F.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428787/
https://ncbi.nlm.nih.gov/pubmed/28386060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00695-7
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