ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress

Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5, a PCNA unloader, plays multiple functions at stalled forks including promoting its restart...

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Pubblicato in:Nat Commun
Autori principali: Park, Su Hyung, Kang, Nalae, Song, Eunho, Wie, Minwoo, Lee, Eun A., Hwang, Sunyoung, Lee, Deokjae, Ra, Jae Sun, Park, In Bae, Park, Jieun, Kang, Sukhyun, Park, Jun Hong, Hohng, Sungchul, Lee, Kyoo-young, Myung, Kyungjae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914801/
https://ncbi.nlm.nih.gov/pubmed/31844045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13667-4
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