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ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress
Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5, a PCNA unloader, plays multiple functions at stalled forks including promoting its restart...
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| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6914801/ https://ncbi.nlm.nih.gov/pubmed/31844045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13667-4 |
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