ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork

R-loops are formed when replicative forks collide with the transcriptional machinery and can cause genomic instability. However, it is unclear how R-loops are regulated at transcription-replication conflict (TRC) sites and how replisome proteins are regulated to prevent R-loop formation or mediate R...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Kim, Sangin, Kang, Nalae, Park, Su Hyung, Wells, James, Hwang, Taejoo, Ryu, Eunjin, Kim, Byung-gyu, Hwang, Sunyoung, Kim, Seong-jung, Kang, Sukhyun, Lee, Semin, Stirling, Peter, Myung, Kyungjae, Lee, Kyoo-young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367208/
https://ncbi.nlm.nih.gov/pubmed/32542338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa501
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi