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ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin
Temporal and spatial regulation of the replication factory is important for efficient DNA replication. However, the underlying molecular mechanisms are not well understood. Here, we report that ATAD5 regulates the lifespan of replication factories. Reduced expression of ATAD5 extended the lifespan o...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542800/ https://ncbi.nlm.nih.gov/pubmed/23277426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201206084 |
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