ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress

Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5, a PCNA unloader, plays multiple functions at stalled forks including promoting its restart...

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Publicado no:Nat Commun
Main Authors: Park, Su Hyung, Kang, Nalae, Song, Eunho, Wie, Minwoo, Lee, Eun A., Hwang, Sunyoung, Lee, Deokjae, Ra, Jae Sun, Park, In Bae, Park, Jieun, Kang, Sukhyun, Park, Jun Hong, Hohng, Sungchul, Lee, Kyoo-young, Myung, Kyungjae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914801/
https://ncbi.nlm.nih.gov/pubmed/31844045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13667-4
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