A carregar...
Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization
Recent clinical studies have revealed that a somatic mutation in MAP2K1, causing constitutive activation of MEK1 in osteogenic cells, occurs in melorheostotic bone disease in humans. We have generated a mouse model which expresses an activated form of MEK1 (MEK1DD) specifically in osteoprogenitors p...
Na minha lista:
| Publicado no: | Bone |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6914252/ https://ncbi.nlm.nih.gov/pubmed/31689526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115106 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|