Canagliflozin, an SGLT2 inhibitor, corrects glycemic dysregulation in TallyHO model of T2D but only partially prevents bone deficits

Higher fracture risk in type 2 diabetes (T2D) is attributed to disease-specific deficits in micro-structural and material properties of bone, although the primary cause is not yet established. The TallyHO (TH) mouse is a polygenic model of early-onset T2D and obesity analogous to adolescent-onset T2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bone
Hauptverfasser: Thrailkill, Kathryn M., Bunn, R. Clay, Uppuganti, Sasidhar, Ray, Philip, Popescu, Iuliana, Kalaitzoglou, Evangelia, Fowlkes, John L., Nyman, Jeffry S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852344/
https://ncbi.nlm.nih.gov/pubmed/32890778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115625
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge