Genetic ablation of SGLT2 function in mice impairs tissue mineral density but does not affect fracture resistance of bone

Selective sodium-dependent glucose co-transporter 2 inhibitors (SGLT2Is) are oral hypoglycemic medications utilized increasingly in the medical management of hyperglycemia among persons with type 2 diabetes (T2D). Despite favorable effects on cardiovascular events, specific SGLT2Is have been associa...

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Publicado no:Bone
Main Authors: Thrailkill, Kathryn M., Bunn, R. Clay, Uppuganti, Sasidhar, Ray, Philip, Garrett, Kate, Popescu, Iuliana, Pennings, Jacquelyn S., Fowlkes, John L., Nyman, Jeffry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059549/
https://ncbi.nlm.nih.gov/pubmed/31991250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115254
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