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SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice

Persons with type 1 and type 2 diabetes have increased fracture risk, attributed to deficits in the microarchitecture and strength of diabetic bone, thought to be mediated, in part, by the consequences of chronic hyperglycemia. Therefore, to examine the effects of a glucose-lowering SGLT2 inhibitor...

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Bibliografiske detaljer
Udgivet i:Bone
Main Authors: Thrailkill, Kathryn M., Bunn, R. Clay, Nyman, Jeffry S., Rettiganti, Mallikarjuna R., Cockrell, Gael E., Wahl, Elizabeth C., Uppuganti, Sasidhar, Lumpkin, Charles K., Fowlkes, John L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679447/
https://ncbi.nlm.nih.gov/pubmed/26211996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.07.025
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