Loss of Insulin Receptor in Osteoprogenitor Cells Impairs Structural Strength of Bone

Type 1 diabetes mellitus (T1D) is associated with decreased bone mineral density, a deficit in bone structure, and subsequently an increased risk of fragility fracture. These clinical observations, paralleled by animal models of T1D, suggest that the insulinopenia of T1D has a deleterious effect on...

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Detalhes bibliográficos
Main Authors: Thrailkill, Kathryn, Bunn, R. Clay, Lumpkin, Charles, Wahl, Elizabeth, Cockrell, Gael, Morris, Lindsey, Kahn, C. Ronald, Fowlkes, John, Nyman, Jeffry S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052184/
https://ncbi.nlm.nih.gov/pubmed/24963495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/703589
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