Osteo-promoting effects of insulin-like growth factor I (IGF-I) in a mouse model of type 1 diabetes

OBJECTIVE: Using a streptozotocin (STZ)-induced mouse model of type 1 diabetes (T1D), we have previously demonstrated that long-term diabetes inhibits regenerative bone formation during tibial distraction osteogenesis (DO) and perturbs skeletal integrity by decreasing cortical thickness, bone minera...

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Bibliografski detalji
Glavni autori: Fowlkes, John L., Nyman, Jeffry, Bunn, R. Clay, Jo, Chanhee, Wahl, Elizabeth C., Liu, Lichu, Cockrell, Gael E., Morris, Lindsey M., Lumpkin, Charles K., Thrailkill, Kathryn M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789626/
https://ncbi.nlm.nih.gov/pubmed/23886838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.07.017
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