Učitavanje...
Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains
[Image: see text] Fragment-based ligand discovery has been successful in targeting diverse proteins. Despite drug-like molecules having more 3D character, traditional fragment libraries are largely composed of flat, aromatic fragments. The use of 3D-enriched fragments for enhancing library diversity...
Spremljeno u:
| Izdano u: | ACS Med Chem Lett |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American
Chemical Society
2019
|
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6912871/ https://ncbi.nlm.nih.gov/pubmed/31857841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00414 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|