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Targeting Cancer Cells with BET Bromodomain Inhibitors

Cancer cells are often hypersensitive to the targeting of transcriptional regulators, which may reflect the deregulated gene expression programs that underlie malignant transformation. One of the most prominent transcriptional vulnerabilities in human cancer to emerge in recent years is the bromodom...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Xu, Yali, Vakoc, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495050/
https://ncbi.nlm.nih.gov/pubmed/28213432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026674
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