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Targeting Cancer Cells with BET Bromodomain Inhibitors

Cancer cells are often hypersensitive to the targeting of transcriptional regulators, which may reflect the deregulated gene expression programs that underlie malignant transformation. One of the most prominent transcriptional vulnerabilities in human cancer to emerge in recent years is the bromodom...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Xu, Yali, Vakoc, Christopher R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495050/
https://ncbi.nlm.nih.gov/pubmed/28213432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026674
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