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Nonequivalent Response to Bromodomain-Targeting BET Inhibitors in Oligodendrocyte Cell Fate Decision
The tandem bromodomains (BD1 and BD2) of the BET family proteins BRD2, BRD3, BRD4 and BRDT, are structurally conserved but not functionally equivalent. In this issue of Chemistry & Biology, Zhou and colleagues report that a BD1-specific chemical inhibitor, Olinone, enhances oligodendrocyte diffe...
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137397/ https://ncbi.nlm.nih.gov/pubmed/25036774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.07.003 |
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