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Nonequivalent Response to Bromodomain-Targeting BET Inhibitors in Oligodendrocyte Cell Fate Decision

The tandem bromodomains (BD1 and BD2) of the BET family proteins BRD2, BRD3, BRD4 and BRDT, are structurally conserved but not functionally equivalent. In this issue of Chemistry & Biology, Zhou and colleagues report that a BD1-specific chemical inhibitor, Olinone, enhances oligodendrocyte diffe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Chiang, Cheng-Ming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137397/
https://ncbi.nlm.nih.gov/pubmed/25036774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.07.003
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