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Targeting Cancer Cells with BET Bromodomain Inhibitors
Cancer cells are often hypersensitive to the targeting of transcriptional regulators, which may reflect the deregulated gene expression programs that underlie malignant transformation. One of the most prominent transcriptional vulnerabilities in human cancer to emerge in recent years is the bromodom...
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| Udgivet i: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495050/ https://ncbi.nlm.nih.gov/pubmed/28213432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026674 |
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