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Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing

CRISPR-Cas9 systems provide powerful tools for genome editing. However, optimal employment of this technology will require control of Cas9 activity so that the timing, tissue specificity, and accuracy of editing may be precisely modulated. Anti-CRISPR proteins, which are small, naturally occurring i...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Garcia, Bianca, Lee, Jooyoung, Edraki, Alireza, Hidalgo-Reyes, Yurima, Erwood, Steven, Mir, Aamir, Trost, Chantel N., Seroussi, Uri, Stanley, Sabrina Y., Cohn, Ronald D., Claycomb, Julie M., Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910239/
https://ncbi.nlm.nih.gov/pubmed/31722192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.017
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