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Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae

Given the widespread use and application of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas gene editing system across many fields, a major focus has been the development, engineering and discovery of molecular means to precisely control and regulate the enzymatic function...

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Pubblicato in:Microbiology (Reading)
Autori principali: Basgall, Erianna M., Goetting, Samantha C., Goeckel, Megan E., Giersch, Rachael M., Roggenkamp, Emily, Schrock, Madison N., Halloran, Megan, Finnigan, Gregory C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Microbiology Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982135/
https://ncbi.nlm.nih.gov/pubmed/29488867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000635
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