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Solution structure and dynamics of anti-CRISPR AcrIIA4, the Cas9 inhibitor
The bacterial CRISPR-Cas system provides adaptive immunity against invading phages. Cas9, an RNA-guided endonuclease, specifically cleaves target DNA substrates and constitutes a well-established platform for genome editing. Recently, anti-CRISPR (Acr) proteins that inhibit Cas9 have been discovered...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832863/ https://ncbi.nlm.nih.gov/pubmed/29497118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22177-0 |
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